Genotoxicity Evaluation of Vaishvanara Churna - A classical Ayurvedic Formulation

Aims: The current study aimed to evaluate the genotoxicity of Vaishvanara Churna, a polyherbal formulation by using Peripheral Blood Mononuclear Cells. was supported content heavy metals in ayurvedic formulation. Background: Churna is classical that used for treating conditions, such as flatulence with gurgling sound (Adhmana), abdominal lump (Gulma); Duodenal ulcer (Parinamasula), Rheumatism (Amavata); heart disease (Hrdroga). Objective: objective on Cells alkaline Single-cell Gel Electrophoresis and correlate possible association number present Methodology: Alkaline Single Cell see effects cells 2% Hydrogen Peroxide standard oxidizing agent. Observation: Cells, isolated from fresh human blood sample, were treated vitro varying concentrations (0.2, 0.4, 0.8, 1.6, 3.2 mg/ml aqueous extract) protocol. It found none assessed toxic Conclusion: simple technique any drug Human Beings, it can be an alternative animal studies.